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pentobarbital will minimize the level or result of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Sturdy CYP3A4 inducers could minimize suvorexant efficacy; if amplified suvorexant dose necessary, usually do not exceed 20 mg/dayWatch Closely (1)pentobarbital will decrease the level or effect of mestranol by